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KMID : 0363320120330020231
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Journal of Korean Oriental Internal Medicine
2012 Volume.33 No. 2 p.231 ~ p.242
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Efficacy of Gamiyukmijihwang-tang on Recurrent Aphthous Stomatitis
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Kim Ju-Yeon
Kim Jin-Sung
Son Ji-Hee
Seon Jong-Ki
Kang Kyung
Jang Seung-Won
Son Ji-Young
Ryu Bong-Ha
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Abstract
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Objectives: This study was designed to investigate the Efficacy of Gamiyukmijihwang-tang on Recurrent Aphthous Stomatitis.
Methods: We surveyed 10 recurrent aphthous stomatitis patients visited the oral diseases clinic in the Kyung Hee University Oriental Medicine Hospital from September, 2011 to March, 2012. Before and 2 weeks after taking Gamiyukmijihwang-tang, the subjects were evaluated on clinical characteristics of recurrent aphthous stomatitis, severity of pain using visual analogue scale (VAS), quality of life about oral health (based on the 14-item Oral Health Impact Profile-14) and yin-deficiency condition (based on the 10-item Yin-deficiency Questionnaire). Then, 5 patients who had already finished treatment were assessed about recurrence of recurrent aphthous stomatitis by telephone survey 6 weeks later.
Results: After 2 weeks taking Gamiyukmijihwang-tang, clinical characteristics of 10 patients of recurrent aphthous stomatitis improved; their severity of pain, quality of life about oral health and yin-deficiency condition improved significantly. After 6 weeks, 3 of 5 patients who had already finished treatment didn’t experience recurrence of recurrent aphthous stomatitis. The other 2 patients experienced a recurrence, but their clinical characteristics of recurrent aphthous stomatitis improved significantly.
Conclusions: Gamiyukmijihwang-tang is effective on recurrent aphthous stomatitis. Studies with a larger number of cases and longer follow-up will be needed in the future.
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KEYWORD
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recurrent aphthous stomatitis, Yukmijihwang-tang (Liuweidihuang-tang)
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